McKeown Medical
167 Bath Street, Glasgow, G2 4SQ
Relfydess is one of the most talked-about and exciting new arrivals in the world of aesthetic medicine, a next-generation botulinum toxin from Galderma. Galderma claims that the 39% of patients see results on the first day, and up to 75% of patients still have improvement at six months. These are considerably better statistics than we would expect with our type-A neurotoxins like Botox, Azzalure, and Bocouture.
Date posted — 26.06.25
At McKeown Medical, we were one of the first UK clinics to introduce Relfydess into clinical practice. However, we wanted to understand how the drug performs and what our patients actually think of it in the real world. Without sounding too cynical, drug companies can usually get clinical trials to say what they want them to, and so we wanted to understand what our patients think of it. In the first two weeks of its release, we treated 97 patients using this new toxin. A couple of weeks later, we sent a survey to all of them, and 51 of them replied. These are the results.
How quickly did Relfydess kick in?
The patients we treated in the first couple of weeks were predominantly patients who had complained of poor results with their previous toxin. Patients were asked to compare the time it took for Relfydess to begin working versus their previous treatments. The responses revealed:
This suggests that Relfydess performs at least as quickly, and often faster, than established toxins in most patients.
When asked, the patient was asked how the aesthetic results of Relfydess compared to previous treatments:
For one patient who was not part of the formal survey, we treated the left side with Relfydess at the standard licensed dose and the other side with Botox at the standard licensed dose. At two weeks, there was a noticeably better reduction in crow’s feet on the Relfydess side compared with the Botox side, which may explain why many patients prefer the aesthetic outcome.
Many patients searching for Botox near me are increasingly asking whether Relfydess could offer superior or longer-lasting results compared with traditional products.
A bit issue around Reflydess is that the injections appear to be more painful than regular toxins.
Was the extra pain worth it?
For the patients who felt it was more painful, we then asked if they thought the enhanced results were worth the additional discomfort.
The majority (42 patients, 88%) said that the additional discomfort was worth it for the better results they have experienced.
All of these patients were treated in the first two weeks we had the product. Since then, we’ve been adding a small amount of local anaesthetic, which seems to be making the treatment more comfortable. We will audit those results and update you on that soon!
And perhaps the most important question of all, will they continue to use Relfydess going forward, or would they prefer to go back to their previous toxin?
It is still too early for us to comment on the longevity of the new product and how that compares, but in terms of early results, our patients seem to be impressed with the new product.
Relfydess appears to offer a real advantage for a specific subset of patients, particularly those who previously reported diminished results from classic botulinum toxins.
However, it’s worth noting that many of the patients who opted to try Relfydess did so because they were dissatisfied with their outcomes from traditional products. This may skew the overall perception in favour of Relfydess, as these patients had a lower baseline of satisfaction. In individuals who already get excellent results from Botox or similar products, the difference may be less pronounced.
For patients actively searching for relfydess wrinkle relaxing injections near me, it is important to understand that suitability depends on prior response, aesthetic goals, and individual anatomy.
A growing concern among long-term users of botulinum toxin is a phenomenon often referred to as “resistance.” While true immunity, where there is no response at all, is very rare, a larger proportion of patients develop partial resistance, where the treatment still works but becomes less effective over time.
In our experience:
However, for the very small number of patients with true immunity (i.e., no effect at all from Botox or similar toxins), we have now treated three such patients with Relfydess, and none of them responded. This suggests that Relfydess may not be effective in cases of complete immunological resistance to botulinum toxin.
Relfydess is an exciting new addition to the aesthetic toolbox. Early results from our patients indicate it may:
We have also observed sustained outcomes, including Relfydess at six months, providing further support for its potential longevity in clinical practice.
However, for those who already do well with established toxins, the benefits may be less obvious. And for patients with complete immunity to botulinum toxin, Relfydess does not appear to overcome this barrier.
If you’ve found that your usual wrinkle treatment isn’t giving you the same results, or you’re curious about whether Relfydess could be a better fit, we’d love to hear from you. Get in touch to book a consultation and find out if this next-generation treatment is right for you.
Call us at 0141 370 0509 or start your consultation.
Loose Skin After Weight Loss or GLP-1 Injections: Why the Right Treatment Varies So Much From Person to Person and...
How Quantum RF Can Help Tighten Loose Arm Skin After GLP-1 Weight Loss
Discover how biostimulators such as Sculptra and Julaine stimulate collagen production to restore firmer, more natural-looking facial support over time.
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Loose Skin After Weight Loss or GLP-1 Injections: Why the Right Treatment Varies So Much From Person to Person and...
How Quantum RF Can Help Tighten Loose Arm Skin After GLP-1 Weight Loss
Discover how biostimulators such as Sculptra and Julaine stimulate collagen production to restore firmer, more natural-looking facial support over time.
...
And this is why we LOVE combination treatments in the clinic!
Different parts of the face age in different ways. And even different layers of the same part sometimes age differently, which is why we often need to combine treatments to achieve the best overall effect for each patient.
This lovely patient first underwent some laser resurfacing to her eyelid area to take away the lines and wrinkles and tighten the skin. Then we used some HA to blend the contour below the eye and cheek. Finally, we addressed the lower part of the face and neck with some Sofwave to tighten the skin and Sculptra to give her more connective tissue support.
She is over the moon with her improvement. What do you think?
The biggest mistake I see after weight loss? People choose a treatment before understanding what`s actually causing their loose skin.
Not all "loose skin" is the same, which is why the right treatment for one person can be completely wrong for another.
If you`ve lost weight and aren`t sure which option is right for you, the first step isn`t choosing a device. It`s getting the right diagnosis.
Looking for some advice? Send us a DM to get started.
The Quantum Lift!
We introduced this new technique only a few weeks ago and, well, it’s going even better than expected. This is one of our patients before and immediately after. I always warn my patients that I cannot give them a surgical facelift result with a procedure that doesn’t involve cutting but honestly, in this case, I think we got pretty close to a facelift result and closer than I was expecting.
First we remove some fat from under the chin and jawline before the quantum goes in to tighten the skin. I have included a picture of the neck after the we had removed fat from both sides, but only applied the quantum to her right side. You can see how much difference there is when I try to pinch the skin. In the non-treated skin I skin still pinch an inch (or two) but on the treated side there is very little to pinch, because the tissues have shrunk down so much.
The patient tolerated the procedure very well under simple local anaesthetic without sedation and we had a nice chat throughout. Afterwards she had a cup of tea and then went home with her husband half an hour later.
I have been very excited about The Quantum Lift for a while, but I’m only getting more excited the more I do. I really believe this is a massive step towards an effective way to rejuvenate the lower face and neck whilst avoiding traditional facelift scars.
Everyone knows we do lots of sophisticated facial work in the clinic. But did you know we also now do a lot of breast work too?
This is one of our patients who wanted breast augmentation. She specifically wanted more upper pole fullness so Kavita selected a 325cc high profile implant from Mentor, but placed them under the muscle to give a more natural take off. Mentor are considered the gold standard for breast implant quality and we only use their implants in the clinic.
The patient is just a few weeks post-op, so there is still a little bit of settling to go but she is already delighted with the shape and size. The key to breast surgery is listening to the patients concerns and then tailoring the procedure to get them the result they want - which is something the very fabulous Miss Kavita excels at.
What do you think?
The SMAS Facelift is back at McKeown Medical!�
Patients tell us all the time that they want to get rid of their jowls and facial sagging, but are hesitant about a lengthy surgical procedure or taking several weeks away from work and social commitments. The SMAS Facelift is an excellent alternative for patients who want meaningful improvement without the bigger commitment. �
It`s a technique that lifts and repositions the deeper tissues of the face while removing excess skin. Until Deep Plane became more popular in the last 10 years, SMAS was the gold standard. Compared with Deep Plane, it takes about 3 hours instead of 6-8, can be done under local anaesthetic, has a shorter recovery, and lower risk of nerve injury. For many patients with moderate facial ageing, it produces excellent, long-lasting results at £12,000, all performed by the phenomenal @bramhallplasticsurgery.�
This is one of our patients who had a SMAS Facelift with eyelid surgery five years ago. She`s maintained her results with HA fillers, like many of our surgical patients do, but otherwise her results are still going strong. That`s what SMAS can give you.
Every face ages differently and every patient has different circumstances. Some need the extensive correction of Deep Plane, especially if they have a heavy neck. Others are better suited to SMAS, particularly if you want a less invasive option with quicker recovery.
The right choice depends on your anatomy, your concerns, and your lifestyle. If you’d like to know more about the SMAS facelift, drop your questions in the comments or send us a DM!
So here she is! The one we’ve all been waiting for 😍 This is Lorraine 5 days after her Quantum lift. She’s still at home recovering because she had her body done too (more on that soon), so she’s not been back in the clinic for proper after photos yet. But she’s already delighted and sending the dreamteam these selfies from home. She’s obviously still very early and a bit swollen, but I think we can all see where this is heading already! I’m very excited for Lorraine… and for all of our lovely patients who are already booked for Quantum. This is a game changer for loose skin!
Thank you to this lovely patient for allowing us to share her upper blepharoplasty results, by the phenomenal @bramhallplasticsurgery .
This patient is 62 and came to us feeling self-conscious about the heaviness and puffiness of her upper eyelids. She`d found herself regularly raising her eyebrows just to lift the skin away from her eyes and had noticed a shadow appearing when she looked upwards and outwards, which was beginning to affect her peripheral vision.
Heavy upper eyelids can really knock people`s confidence, especially in social situations and in photos, and yet it`s one of the most straightforward areas to address.
The procedure itself takes around 45–60 minutes and is carried out while patients are awake under local anaesthetic. The scars sit within the natural crease of the eyelid, making them almost impossible to spot once healed
This is just 2.5 months post-surgery, and her scars are already settling beautifully. They`ll continue to fade over the next 12 months.
What do you think?
Yesterday was a big day in the clinic! We officially launched the game changing Quantum RF technology in the clinic. Quantum allows us to take liposuction to another level. We’ve got power assisted lipo which allows us to sculpt more, we’ve got ultrasound assisted lipo which allows us to melt the fat for more gentle removal. Now we’ve got quantum that allows us to follow this up with a treatment to shrink the skin down. It means patients who may previously have needed excisional surgery - like tummy tuck, or arm lift or thigh lift or even facelift - can be successfully treated without long scars. This is truly game changing technology and we are so excited to be the first in Scotland to introduce it. Can you guess who our first patient was? 👀
Here`s a wee update on this lovely patient who is now further along in her Regenerative Facelift journey.
We have combined Juläine PLLA and Sofwave ultrasound skin tightening, and you can see exactly what that pairing delivers: softer contours, improved structure, and a natural-looking result that`s still continuing to develop.
Juläine works by stimulating the body`s own collagen production, gradually restoring structure and support from within. Sofwave works alongside that by firming and lifting the skin at a deeper level. Together, they address the scaffold and the skin.
She`s looking fresher and is absolutely delighted. What do you think?
And if you`ve been thinking about a non-surgical approach to facial rejuvenation, what questions do you have? Drop them below.