McKeown Medical
167 Bath Street, Glasgow, G2 4SQ
Relfydess is one of the most talked-about and exciting new arrivals in the world of aesthetic medicine, a next-generation botulinum toxin from Galderma. Galderma claims that the 39% of patients see results on the first day, and up to 75% of patients still have improvement at six months. These are considerably better statistics than we would expect with our type-A neurotoxins like Botox, Azzalure, and Bocouture.
Date posted — 26.06.25
At McKeown Medical, we were one of the first UK clinics to introduce Relfydess into clinical practice. However, we wanted to understand how the drug performs and what our patients actually think of it in the real world. Without sounding too cynical, drug companies can usually get clinical trials to say what they want them to, and so we wanted to understand what our patients think of it. In the first two weeks of its release, we treated 97 patients using this new toxin. A couple of weeks later, we sent a survey to all of them, and 51 of them replied. These are the results.
How quickly did Relfydess kick in?
The patients we treated in the first couple of weeks were predominantly patients who had complained of poor results with their previous toxin. Patients were asked to compare the time it took for Relfydess to begin working versus their previous treatments. The responses revealed:
This suggests that Relfydess performs at least as quickly, and often faster, than established toxins in most patients.
When asked, the patient was asked how the aesthetic results of Relfydess compared to previous treatments:
For one patient who was not part of the formal survey, we treated the left side with Relfydess at the standard licensed dose and the other side with Botox at the standard licensed dose. At two weeks, there was a noticeably better reduction in crow’s feet on the Relfydess side compared with the Botox side, which may explain why many patients prefer the aesthetic outcome.
Many patients searching for Botox near me are increasingly asking whether Relfydess could offer superior or longer-lasting results compared with traditional products.
A bit issue around Reflydess is that the injections appear to be more painful than regular toxins.
Was the extra pain worth it?
For the patients who felt it was more painful, we then asked if they thought the enhanced results were worth the additional discomfort.
The majority (42 patients, 88%) said that the additional discomfort was worth it for the better results they have experienced.
All of these patients were treated in the first two weeks we had the product. Since then, we’ve been adding a small amount of local anaesthetic, which seems to be making the treatment more comfortable. We will audit those results and update you on that soon!
And perhaps the most important question of all, will they continue to use Relfydess going forward, or would they prefer to go back to their previous toxin?
It is still too early for us to comment on the longevity of the new product and how that compares, but in terms of early results, our patients seem to be impressed with the new product.
Relfydess appears to offer a real advantage for a specific subset of patients, particularly those who previously reported diminished results from classic botulinum toxins.
However, it’s worth noting that many of the patients who opted to try Relfydess did so because they were dissatisfied with their outcomes from traditional products. This may skew the overall perception in favour of Relfydess, as these patients had a lower baseline of satisfaction. In individuals who already get excellent results from Botox or similar products, the difference may be less pronounced.
For patients actively searching for relfydess wrinkle relaxing injections near me, it is important to understand that suitability depends on prior response, aesthetic goals, and individual anatomy.
A growing concern among long-term users of botulinum toxin is a phenomenon often referred to as “resistance.” While true immunity, where there is no response at all, is very rare, a larger proportion of patients develop partial resistance, where the treatment still works but becomes less effective over time.
In our experience:
However, for the very small number of patients with true immunity (i.e., no effect at all from Botox or similar toxins), we have now treated three such patients with Relfydess, and none of them responded. This suggests that Relfydess may not be effective in cases of complete immunological resistance to botulinum toxin.
Relfydess is an exciting new addition to the aesthetic toolbox. Early results from our patients indicate it may:
We have also observed sustained outcomes, including Relfydess at six months, providing further support for its potential longevity in clinical practice.
However, for those who already do well with established toxins, the benefits may be less obvious. And for patients with complete immunity to botulinum toxin, Relfydess does not appear to overcome this barrier.
If you’ve found that your usual wrinkle treatment isn’t giving you the same results, or you’re curious about whether Relfydess could be a better fit, we’d love to hear from you. Get in touch to book a consultation and find out if this next-generation treatment is right for you.
Call us at 0141 370 0509 or start your consultation.
How Quantum RF Can Help Tighten Loose Arm Skin After GLP-1 Weight Loss
Discover how biostimulators such as Sculptra and Julaine stimulate collagen production to restore firmer, more natural-looking facial support over time.
...
Discover what truly works for natural skin tightening, including Morpheus8, BBL SkinTyte, and Sofwave, and how advanced collagen stimulation restores...
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How Quantum RF Can Help Tighten Loose Arm Skin After GLP-1 Weight Loss
Discover how biostimulators such as Sculptra and Julaine stimulate collagen production to restore firmer, more natural-looking facial support over time.
...
Discover what truly works for natural skin tightening, including Morpheus8, BBL SkinTyte, and Sofwave, and how advanced collagen stimulation restores...
Quantum Liposuction! I am SUPER excited to let you know we will be the first in Scotland to offer what is now regarded internationally as the new gold standard technique in liposuction.
We are making a big investment to bring a whole range of cutting edge technology to the clinic to allow us to take our liposuction and body contouring work to the next level.
First we melt the fat using ultrasound. Next we use power assisted liposuction to remove the fat. Finally, we use Quantum RF to tighten the skin. Quantum RF is the new innovation that is taking the body contouring world by storm. It’s an excellent option for patients who need more than a bit of liposuction, but aren’t quite ready for full tummy tuck or arm lift or thigh lift.
Dr Kavita will be doing all of the body contouring procedures under sedation, which means you will be asleep throughout. I will also be using the technology to help shape the jawline and chin and lift the jowls. You can read more about the treatment at the link in our bio.
Let us know what you think in the comments below!
Let`s talk about Mounjaro / Ozempic face!
It feels like everyone is on weight loss drugs right now, and they`re incredible for transforming bodies and health, but rapid weight loss has a real impact on the face.
This lovely patient lost an incredible 6 stones in just twelve months on Mounjaro and loved the results, but felt the life had been sucked out of her face. She naturally had a fuller, more plump face that looked youthful but the rapid weight loss diminished that.
There`s a lot of conversation right now about the best way of tackling it aesthetically and there are different options available. However, since loss of volume is the key driver of the changes, restoring the volume needs to be a central component of how we treat it - which is exactly what we did here.
This is the patient a couple of weeks after 10mls of HA filler in the mid and lower face. She is over the moon that she now has the body and health profile she wanted, but got her face back too!
The best of both worlds. What do you think?
Here’s another gorgeous upper blepharoplasty result from our phenomenal surgeon, @bramhallplasticsurgery.
This patient is 62 years old and came to us for upper eyelid surgery just 2.5 months ago. Russell performed the procedure while she was awake with just a few numbing injections. Here at the clinic we can offer facial surgery with local anaesthetic for those who want to remain awake, or with deep sedation for anyone who’d prefer to sleep throughout (without the downsides of general anaesthetic!)
Thank you to this patient for allowing us to share her fabulous result - her scars are already settling beautifully and will continue to fade over the next 12 months.
What do you think?
Our resident superstar breast surgery expert Dr Kavita was asked to talk about trends in breast surgery on BBC Radio Scotland today. This was Kavita’s first ever live interview and we thought she nailed it!
What do you think?
And this is why combination treatments always win!
This lovely patient is in her 50s and was noticing all of the classic signs of ageing. She was starting to see some jowls forming, the neck was becoming more saggy and she felt she was looking tired.
At this stage in the ageing process it is not one thing that is responsible for causing the tired expression, its a combination of changes that are working together which is why we need a combination of treatments to target it effectively.
We did some sofwave treatment first to tighten the skin on the face and neck. Sofwave is very effective at tightening the skin, but remember: the skin is only the outer layer of the face, so we supported the treatment with some volume replacement in the deeper layers.
I decided to post her selfie style before and afters as well as her clinical pictures so you can see how it looks in real life, as well as the clinical up-close detail. The patient is over the moon with her results.
What do you think?
Here is another beautifully balanced deep plane face and neck lift by the skilful @bramhallplasticsurgery.
The deep plane technique, as the name suggests, works at a deeper level, repositioning the underlying structures of the face and neck rather than simply tightening the skin. By addressing the deeper tissues, we can restore more natural proportions, refine the jawline, and create a smoother, more defined contour beneath the chin - especially when the patient moves or bends their neck forward.
To achieve this impressive improvement in the neck, even in flexion, Russell reduced the deep fat (from under the muscle), trimmed and shaped the salivary glands and reconstructed the muscles of the neck to create a rejuvenated result. This is a much more sophisticated procedure compared with a standard face and neck lift.
At just 2 months post-op, her result is already beautifully balanced. The jawline is sharper, the neck more sculpted, and everything sits in harmony with the rest of her features. Scars are settling well and will continue to soften over time.
She may choose to refine things further with laser resurfacing for skin quality and subtle volume restoration in the mid-face, but even at this stage, the transformation speaks for itself.
Thank you to our patient for allowing us to share her journey.
What do you think?
Thank you to this lovely patient for allowing us to share her beautiful result from the talented @bramhallplasticsurgery.
This patient is just 2.5 months after upper eyelid surgery, and already looking incredibly fresh and natural. The scars are settling very well and will continue to soften over the coming months.
The incisions are carefully placed within the natural eyelid crease, making them very difficult to see once healed. Excess skin has been removed to open up the eye area, while maintaining a soft, natural appearance.
A small amount of muscle was reduced at the outer part of the eyelid to address hooding, without affecting the central area. This helps preserve a youthful fullness above the eye. There has also been a conservative reduction of the lateral brow fat to further refine the contour. This highly tailored, bespoke approach to surgery is the attention to detail that lies at the heart of our clinic’s approach and philosophy.
As with many patients, her anatomy meant these changes developed earlier than expected. In the right cases, surgery at a younger age can deliver a subtle but very impactful improvement.
What do you think?
Happy Easter from our excited little bunnies 🐣🐰
Thank you to our lovely patient for allowing us to share these photos.
This is just 4 weeks after her first session (of three) with Juläine and we’re already starting to see a soft return of fullness and improvement in skin quality.
Juläine is not a traditional filler. It works by stimulating your body’s own collagen production, gradually restoring structure, firmness and elasticity from within.
This is just the beginning. As collagen continues to rebuild over the coming weeks and months, results will become more noticeable with improved support, smoother contours and a natural, refreshed appearance.
The patient is delighted with her progress so far. What do you think?